Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0316412
PubChem CID
Molecular Formula
C13H11N3O2
Molecular Weight
241.25 g/mol
Synonyms/Alias
InChI Key
PQHURGADVOOPAU-IZZDOVSWSA-N
InChI
InChI=1S/C13H11N3O2/c1-16-11(12(17)15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-7,14H,1H3,(H,15,17,18)/...
IUPAC Name
(5E)-5-(1H-indol-3-ylmethylidene)-1-methylimidazolidine-2,4-dione
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

18 20 0 0 0 0 0 0 0 0999 V2000
-3.2283 2.5739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.1103 1.0785 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
-1.8312 0...

Experimental Data

Activity Data

Target Ion Channel
Glycine receptor subunit alpha-3
Uniprot Accession Number
Function
Modulator
Species
Homo sapiens (Human)
IC50
IC50: 33900 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not mention mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
18
Rotatable Bonds
1
logP
1.6904
Complexity
67.5774
TPSA (Ų)
65.2
H-Bond Donors
2
H-Bond Acceptors
2
Ring Count
3
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